May 9, 2023

 

VIA FACSIMILE AND EDGAR

 

U.S. Securities and Exchange Commission

Division of Corporate Finance

Washington, DC 20549

 

  Re: Ensysce Bioscience, Inc.
    Registration Statement on Form S-1 (Registration No. 333-271480) -
    Concurrence in Acceleration Request

 

Ladies and Gentlemen:

 

H.C. Wainwright & Co., LLC (“Wainwright”), solely acting as placement agent on a best-efforts basis in an offering pursuant to the registration statement on Form S-1 (333-271480) (the “Registration Statement”), hereby concurs in the request by Ensysce Bioscience, Inc. that the effective date of the above-referenced registration statement be accelerated to 5:00 P.M. Eastern Time on Tuesday, May 9, 2023, or as soon as practicable thereafter, pursuant to Rule 461 under the Securities Act. Wainwright affirms that it is aware of its obligations under the Securities Act as they pertain to the best efforts offering pursuant to the Registration Statement.

 

  Very truly yours,
     
  H.C. WAINWRIGHT & CO., LLC
     
  By: /s/ Edward D. Silvera
  Name:  Edward D. Silvera
  Title: Chief Operating Officer

 

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