Exhibit 107

Calculation of Filing Fee Tables

Form S-3
(Form Type)

Ensysce Biosciences, Inc.
(Exact Name of Each Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

		Security Type		Security Class Title		Fee Calculation or Carry Forward Rule		Amount Registered(1)				Proposed Maximum Offering Price Per Unit(2)				Maximum Aggregate Offering Price				Fee Rate				Amount of Registration Fee				Carry Forward Form Type				Carry Forward File Number				Carry Forward Initial effective date				Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to Be Paid		Equity		Common stock, par value $0.0001 per share, underlying secured convertible notes		Rule 457(c)			5,000,000	⁽³⁾		$	0.98			$	4,900,000				0.00011020			$	540
		Equity		Common stock, par value $0.0001 per share, underlying warrants		Rule 457(c)			522,094				0.98				511,653				0.00011020				57
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities		Equity		Common stock, par value $0.0001 per share, underlying warrants		Rule 415(a)(6)			9,335,780				0.5994			$	5,595,867				0.0000927			$	519				S-3				333-266338				August 4, 2022			$	57
		Total Offering Amounts														$								$	597
		Total Fees Previously Paid																						$	519
		Total Fee Offsets																						$	57
		Net Fee Due														$								$	540

(1)	The shares of the Registrant’s common stock, par value $0.0001 per share (the “Common Stock”), offered hereby also include such presently indeterminate number of shares of Common Stock as a result of stock splits, stock dividends or similar transactions in accordance with Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”). The Registrant effected a 1 for 20 reverse stock split in October 2022.

(2)	Pursuant to Rule 457(c) under the Securities Act, and solely for the purpose of calculating the registration fee, the proposed maximum offering price per share is $0.98, which is the average of the high and low prices of the Common Stock as reported on The NASDAQ Capital Market on December 13, 2022, which date is within five business days prior to filing this Registration Statement. The Registrant effected a 1 for 20 reverse stock split in October 2022.

(3)	Represents the resale of shares of Common Stock issuable or potentially issuable upon the conversion of certain secured convertible 6% original issue discount promissory notes in the aggregate principal amount remaining of $3,905,264 (after giving effect to the 6% original issue discount and partial conversion of the original aggregate principal amount of $8,480,000 previously registered) that were issued to investors in certain private transactions described herein, plus interest thereon at the rate of 6% per annum based on a conversion price of $0.98 (after giving effect to certain potential anti-dilution adjustments), which is the average of the high and low prices of the Common Stock as reported on The NASDAQ Capital Market on December 13, 2022, which date is within five business days prior to filing this Registration Statement.

(4)	Represents the resale of shares of Common Stock issuable or potentially issuance upon the exercise, at an exercise price of $0.98 per share, of certain warrants to purchase shares of Common Stock that were issued to investors in certain private transactions described herein (after giving effect to certain potential anti-dilution adjustments), which is the average of the high and low prices of the Common Stock as reported on The NASDAQ Capital Market on December 13, 2022, which date is within five business days prior to filing this Registration Statement.