Exhibit 21
Subsidiaries of Ensysce Biosciences, Inc.
| Legal Entity* | Jurisdiction of Organization | |
| EBIR, Inc.** (79.2%) | Delaware | |
| EBI OpCo, Inc. | Delaware | |
| EBI Operating, Inc. | Delaware |
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* Unless otherwise noted, reflects 100% ownership by Ensysce Biosciences, Inc.
** Formerly known as Covistat, Inc.