Exhibit
23.3
CONSENT
OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We
consent to the inclusion in this Amendment No. 1 to Registration Statement on Form S-1 of our report dated March 15, 2021 (except
for the exchange ratio as detailed in Note 12, as to which the date is September 21, 2021), with respect to the consolidated financial
statements of Ensysce Biosciences, Inc. as of December 31, 2020 and 2019 and for the years then ended (which report includes an explanatory
paragraph regarding the existence of substantial doubt about the Company’s ability to continue as a going concern), and to
the reference to us under the heading “Experts” included in the prospectus, which is part of this Registration Statement.
/s/
Mayer Hoffman McCann P.C.
San
Diego, California
September
21, 2021